GCHFR Antibody / GFRP
GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. Cross-linking experiments have shown that GFRP is usually expressed as a homodimer or pentamer.
Product Specifications
UniProt
P30047
Host
Mouse
Immunogen
A recombinant fragment of human GCHFR protein was used as the immunogen for the GCHFR antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Applications
WB, IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the GCHFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This GCHFR antibody is available for research use only.
CAS Number
9007-83-4
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