Oteseconazole
Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes[1][2].
Product Specifications
CAS Number
1340593-59-0
Product Name Alternative
VT-1161
UNSPSC
12352005
Hazard Statement
H228, H315, H319
Target
Cytochrome P450; Fungal
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/oteseconazole.html
Concentration
10mM
Purity
99.60
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
O[C@@](CN1C=NN=N1)(C(C=CC(F)=C2)=C2F)C(F)(C3=CC=C(C4=CC=C(OCC(F)(F)F)C=C4)C=N3)F
Molecular Formula
C23H16F7N5O2
Molecular Weight
527.39
Precautions
H228, H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
CYP2C19; CYP2C9; CYP51
Available Sizes
Frequently Asked Questions
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