HIV-1 inhibitor-15
Product Specifications
UNSPSC Description
HIV-1 inhibitor-15 (compound 9d) is a highly potent and broad-spectrum HIV-1 inhibitor. HIV-1 inhibitor-15 has inhibitory activity against HIV-1 WT, L100I, K103N, Y181C, E138K with EC50s of 1.7 nM, 4 nM, 2 nM, 6 nM and 9 nM, respectively. HIV-1 inhibitor-15 has good solubility, safety profiles and favorable oral bioavailability[1].
Target Antigen
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-15.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(NC2=NC=CC(NC3=C(C)C=C(C4=CC=NC=C4)C=C3C)=N2)C=C1
Molecular Weight
392.46
References & Citations
[1]Ding L, et al. Discovery of Novel Pyridine-Dimethyl-Phenyl-DAPY Hybrids by Molecular Fusing of Methyl-Pyrimidine-DAPYs and Difluoro-Pyridinyl-DAPYs: Improving the Druggability toward High Inhibitory Activity, Solubility, Safety, and PK. J Med Chem. 2022;65(3):2122-2138.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144122/HIV-1-inhibitor-15-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144122/
Clinical Information
No Development Reported
CAS Number
2757182-99-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1039442 Inquire
Recombinant Saccharomyces cerevisiae Elongation of fatty acids protein 2 (FEN1)
Ask
View Details