6-Deoxyjacareubin
6-Deoxyjacareubin is a natural xanthone, that can be isolated from the leaves of Vismia latifolia. 6-Deoxyjacareubin protects against non-apoptotic cell death by inhibiting ROS production. 6-Deoxyjacareubin ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis (ALS) [1].
Product Specifications
CAS Number
[16265-56-8]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/6-deoxyjacareubin.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(OC3=C1C=CC=C3O)C=C4C(C=CC(C)(C)O4)=C2O
Molecular Formula
C18H14O5
Molecular Weight
310.30
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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