GPR40 agonist 6

GPR40 agonist 6 (Compound 7a) is a potent and selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist with an EC50 of 0.058 μM[1].

Product Specifications

CAS Number

[1798751-25-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Free Fatty Acid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gpr40-agonist-6.html

Purity

98.81

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CC1=C(COC2=CC=C(CCC(O)=O)C=C2)N=C(C3=CC=CC=C3)O1

Molecular Formula

C20H19NO4

Molecular Weight

337.37

Precautions

H302, H315, H319, H335

References & Citations

[1]Zahanich I, et al. Phenoxymethyl 1,3-oxazoles and 1,2,4-oxadiazoles as potent and selective agonists of free fatty acid receptor 1 (GPR40) . Bioorg Med Chem Lett. 2015 Aug 15;25 (16) :3105-11.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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