GPR40 agonist 6
GPR40 agonist 6 (Compound 7a) is a potent and selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist with an EC50 of 0.058 μM[1].
Product Specifications
CAS Number
[1798751-25-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gpr40-agonist-6.html
Purity
98.81
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC1=C(COC2=CC=C(CCC(O)=O)C=C2)N=C(C3=CC=CC=C3)O1
Molecular Formula
C20H19NO4
Molecular Weight
337.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Zahanich I, et al. Phenoxymethyl 1,3-oxazoles and 1,2,4-oxadiazoles as potent and selective agonists of free fatty acid receptor 1 (GPR40) . Bioorg Med Chem Lett. 2015 Aug 15;25 (16) :3105-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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