Phenylglyoxylic acid-d5 (sodium)

Phenylglyoxylic acid-d5 (Benzoylformic acid-d5) sodium is the deuterium labeled Phenylglyoxylic acid sodium (HY-W010255A) . Phenylglyoxylic acid (Benzoylformic acid) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid can be used as drug intermediate for synthesis of antineoplastic compounds[1][2].

Product Specifications

CAS Number

[2708283-39-8]

Product Name Alternative

Benzoylformic acid-d5 (sodium) ; Sodium phenylglyoxylate-d5

UNSPSC

12352005

Target

Drug Intermediate; Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Inflammation/Immunology

Purity

99.79

Solubility

H2O : ≥ 100 mg/mL

Smiles

OC(C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O)=O.[Na]

Molecular Formula

C8HD5NaO3

Molecular Weight

178.15

References & Citations

[1]Capella KM, et al. Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid: NHANES 2005-2006 and 2011-2012. Environ Res. 2019 Apr;171:101-110.|[2]Leont'eva L I, et al. Antiinflammatory activity of derivatives of phenylglyoxylic acid[J]. Pharmaceutical Chemistry Journal, 1993, 27 (3) : 195-197.|[3]Jiang W, et al., Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties. Bioorg Chem. 2020 Jan;94:103402.