GBA2 antibody
Product Specifications
Background
Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide(GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.
Synonyms
Non-lysosomal glucosylceramidase (NLGase)|Beta-glucocerebrosidase 2 (Beta-glucosidase 2)|Bile acid beta-glucosidase GBA2|Bile acid glucosyl transferase GBA2|Cholesterol glucosyltransferase GBA2|Cholesteryl-beta-glucosidase GBA2|Glucosylceramidase 2|Non-lysosomal cholesterol glycosyltransferase|Non-lysosomal galactosylceramidase|Non-lysosomal glycosylceramidase|GBA2|KIAA1605|SPG46
Gene ID
57704
UniProt
Q9HCG7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
glucosidase, beta(bile acid) 2
Target
GBA2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA
Field of Research
Metabolism
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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