Subasumstat
Subasumstat (TAK-981) is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities[1][2].
Product Specifications
CAS Number
[1858276-04-6]
Product Name Alternative
TAK-981
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/TAK-981.html
Purity
98.56
Solubility
DMSO : 200 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=CC([C@@H]4NCCC5=C4C=C(Cl)C=C5)=C(C)S3)=O)C1)(N)=O
Molecular Formula
C25H28ClN5O5S2
Molecular Weight
578.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Sumoylation inhibitor TAK-981.|[2]TAK-981.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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