3-O-cis-p-Coumaroyl maslinic acid
Product Specifications
UNSPSC Description
3-O-cis-p-Coumaroyl maslinic acid (compound 16) is a natural compound isolated from the ethyl acetate extract of leaves of Miconia albicans.3-O-cis-p-Coumaroyl maslinic acid can inhibit PTP1B, with the IC50 of 0.46 μM, and shows antimicrobial activity on Gram-positive bacteria and yeasts[1][2].
Target Antigen
Bacterial; Phosphatase
Type
Natural Products
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/3-o-cis-p-coumaroyl-maslinic-acid.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](C(C)([C@@]([H])([C@@]2(C1)C)CC[C@@]3([C@@]2(CC=C4[C@]3(CC[C@@]5([C@]4(CC(C)(CC5)C)[H])C(O)=O)C)[H])C)C)OC(/C=C\C6=CC=C(C=C6)O)=O
Molecular Weight
618.84
References & Citations
[1]de Cássia Lemos Lima R, et al. High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans. Molecules. 2018;23(7):1755.|[2]Braca A, et al. Antimicrobial triterpenoids from Licania heteromorpha. Planta Med. 2000;66(8):768-769.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N7165/3-O-cis-p-Coumaroyl-maslinic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N7165/
Clinical Information
No Development Reported
CAS Number
69297-40-1
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