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PD-1/PD-L1-IN-46

PD-1/PD-L1-IN-46 (compound (R) -C27) is an PD-1/PD-L1 antagonist with IC50 value of 18.66 nM[1].

Product Specifications

UNSPSC

12352005

Target

PD-1/PD-L1

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pd-1-pd-l1-in-46.html

Smiles

ClC1=C(C=CC=C1C2=CC=CC=C2)[C@@H]3OC4=C(CC3)C(OCC5=CC=CN=C5)=C(CNCCO)C=C4Cl

Molecular Formula

C30H28Cl2N2O3

Molecular Weight

535.46

References & Citations

[1]Luosen Wang, et al. Design, Synthesis, and Biological Evaluation of Chroman Derivatives as PD-1/PD-L1 Antagonists. J Chem Inf Model. 2024 Jun 24;64 (12) :4877-4896.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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