PD-1/PD-L1-IN-46
PD-1/PD-L1-IN-46 (compound (R) -C27) is an PD-1/PD-L1 antagonist with IC50 value of 18.66 nM[1].
Product Specifications
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-1-pd-l1-in-46.html
Smiles
ClC1=C(C=CC=C1C2=CC=CC=C2)[C@@H]3OC4=C(CC3)C(OCC5=CC=CN=C5)=C(CNCCO)C=C4Cl
Molecular Formula
C30H28Cl2N2O3
Molecular Weight
535.46
References & Citations
[1]Luosen Wang, et al. Design, Synthesis, and Biological Evaluation of Chroman Derivatives as PD-1/PD-L1 Antagonists. J Chem Inf Model. 2024 Jun 24;64 (12) :4877-4896.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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