Recombinant Mouse IL13RA1 Protein (Fc Tag)
Product Specifications
Background
Interleukin-13 receptor subunit alpha-1 (IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TRAF3IP1 and binds with low affinity to interleukin-13 (IL3) . IL-13RA1, together with IL4RA, can form a functional receptor for IL13. It also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. The WSXWS motif in domains appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
Abbreviation
IL13RA1
Synonyms
IL-13 R alpha; Novel cytokine receptor; Interleukin-13 receptor subunit alpha; CD213a; IL-13RA; CD213a1; IL-13 R alpha 1; IL-13RA1; Interleukin-13 receptor subunit alpha-1; Interleukin-13-binding protein; Novel cytokine receptor 4; NR4; Il13r; Il13ra; Il13ra1; IL-13R&alpha-1-1; AI882074; IL-13r[a]
UniProt
O09030
Accession Number
O09030
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Ala25-Thr340
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/pdghu9
Product MSDS
https://789.bio/eb/qPKKWD
Calculated Molecular Weight
63.0 kDa
Observed Molecular Weight
80-120 kDa
Species
Mouse
Available Sizes
Curated Selection
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