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Bromodomain inhibitor-8

Bromodomain inhibitor-8 (Intermediate 21) is a BET bromodomain inhibitor for treating autoimmune and inflammatory diseases[1].

Product Specifications

CAS Number

1300031-70-2

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bromodomain-inhibitor-8.html

Concentration

10mM

Purity

98.02

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OC)C1=CC=C(C2=CC3=C(N(C(C)=O)[C@@H](C)C[C@H]3NC4=CC=C(Cl)C=C4)C=C2)C=C1

Molecular Formula

C26H25ClN2O3

Molecular Weight

448.94

References & Citations

[1]CHUNG, Chun-Wa, et al. BROMODOMAIN INHIBITORS FOR TREATING AUTOIMMUNE AND INFLAMMATORY Dl SEASES. WO 2011/054843 Al.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Brd

Available Sizes

Frequently Asked Questions

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