MA-PEG4-VC-PAB-DMEA-duocarmycin DM (TFA)
MA-PEG4-VC-PAB-DMEA-duocarmycin DM TFA is a drug-linker conjugate for ADC by using the DNA minor-groove alkylator Duocarmycin DM , linked via MA-PEG4-vc-PAB-DMEA (HY-126668).
Product Specifications
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ma-peg4-vc-pab-dmea-duocarmycin-dm-tfa.html
Purity
99.84
Smiles
O=C(O)C(F)(F)F.O=C(NCCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(N(CCN(C(OC2=CC3=C([C@@H](CN3C(C4=CC5=CC(OCCN(C)C)=CC=C5N4)=O)CCl)C6=CC=CC=C26)=O)C)C)=O)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)CCN7C(C=CC7=O)=O
Molecular Formula
C70H90ClF3N12O19
Molecular Weight
1495.98
References & Citations
[1]Patil PC, et al. A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents. Anticancer Agents Med Chem. 2015;15 (5) :616-30.|[2]Italo Beria, et al. New alkylating agents. Franch, WO2013149948A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents
Available Sizes
Frequently Asked Questions
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