CD81/TAPA-1
Product Specifications
Gene Name
[CD81]
NCBI Gene ID
975
Reactivity
Human, Mouse, Rat. Others not known.
Storage Conditions
Antibody with azide - store at 2 to 8 degree C.<br>Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
Other Gene Names
[CD81; CD81; S5.7; CVID6; TAPA1; TSPAN28; TAPA1; TSPAN28; Tspan-28]
Short Name
[CD81/TAPA-1]
Other Product Names
[CD81 antigen isoform 2; CD81 antigen; CD81 antigen; CD81 molecule; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28; Tspan-28; CD_antigen: CD81]
NCBI GI Number
663071018
NCBI Accession Number
NP_001284578.1
NCBI GB Accession Number
NM_001297649.1
Uniprot Accession Number
P60033
Available Sizes
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