DSP, Human (His-SUMO)

DSP proteins are major components of desmosomes and are critical for the structural integrity of various tissues. In cardiomyocytes, DSP regulates profibrotic gene expression through MAPK14/p38 MAPK activation and increased TGFB1 protein. DSP Protein, Human (His-SUMO) is the recombinant human-derived DSP protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of DSP Protein, Human (His-SUMO) is 223 a.a., with molecular weight of ~42.1 kDa.

CSDCLMRAEL IVQPELKYGD GIQLTRSREL DECFAQANDQ MEILDSLIRE MRQMGQPCDA YQKRLLQLQE QMRALYKAIS VPRVRRASSK GGGGYTCQSG SGWDEFTKHV TSECLGWMRQ QRAEMDMVAW GVDLASVEQH INSHRGIHNS IGDYRWQLDK IKADLREKSA IYQLEEEYEN LLKASFERMD HLRQLQNIIQ ATSREIMWIN DCEEEELLYD WSD