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Citrulline-specific probe-biotin

Citrulline-specific probe-biotin is a biotinylated probe for detection of citrulline. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD) . PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-biotin is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis[1].

Product Specifications

CAS Number

2468149-70-2

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/citrulline-specific-probe-biotin.html

Smiles

O=CC(C1=CC=CC(NC(C(C)N(N=N2)C=C2CCCC(NCCNC(CCCC[C@H]3[C@]4([H])[C@](NC(N4)=O)([H])CS3)=O)=O)=O)=C1)=O

Molecular Formula

C29H38N8O6S

Molecular Weight

626.73

References & Citations

[1]Bicker K L, et al. Seeing citrulline: development of a phenylglyoxal-based probe to visualize protein citrullination[J]. Journal of the American Chemical Society, 2012, 134 (41) : 17015-17018.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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