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FEN1-IN-4

FEN1-IN-4 (Compound 2) is a human flap endonuclease-1 (hFEN1) inhibitor[1].

Product Specifications

CAS Number

[1995893-58-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

FLAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fen1-in-4.html

Purity

99.86

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N1O)N(CC2CC2)C3=C(C=CC=C3)C1=O

Molecular Formula

C12H12N2O3

Molecular Weight

232.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Jack C Exell, et al. Cellularly Active N-hydroxyurea FEN1 Inhibitors Block Substrate Entry to the Active Site. Nat Chem Biol. 2016 Oct;12 (10) :815-21.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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