(2R) -Octyl-α-hydroxyglutarate-d17
(2R) -Octyl-α-hydroxyglutarate-d17 ((2R) -Octyl-2-HG-d17) is deuterium labeled (2R) -Octyl-α-hydroxyglutarate (HY-103641) . (2R) -Octyl-α-hydroxyglutarate is a modified form of S-isomer 2-Hydroxyglutarate[1].
Product Specifications
CAS Number
[2748638-78-8]
Product Name Alternative
(2R) -Octyl-2-HG-d17
UNSPSC
12352211
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OC(CC[C@H](C(OC([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])=O)O)=O
Molecular Formula
C13H7D17O5
Molecular Weight
277.43
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Sulkowski PL, et al. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologousrecombination and induces PARP inhibitor sensitivity. Sci Transl Med. 2017 Feb 1;9 (375) .
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103641AS1/
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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