TK-642
Product Specifications
CAS Number
2765183-10-4
Target
Phosphatase
Related Pathways
Metabolism
Bioactivity
TK-642 is a potent and selective SHP2 inhibitor with oral activity, based on pyrazole and pyrazine structures (IC50 = 2.7 nmol/L) . It effectively inhibits the proliferation of esophageal carcinoma cells and induces apoptosis, making it useful for studying esophageal cancer.
Smiles
ClC=1C=NC=CC1SC2=NNC=3N=C(C=NC23)N4CCC(C)(CN)CC4
Molecular Formula
C17H20ClN7S
Molecular Weight
389.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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