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Biotinylated Human Claudin-18.2 Protein, His, Avitag™&Flag Tag (Detergent)

Claudin-18.2 is a member of the tight junction protein family. Under physiological conditions, it is only expressed at low levels in the differentiated epithelial cells of the gastric mucosa; whereas under pathological conditions, it exhibits abnormally high expression in various tumors such as gastric cancer and pancreatic cancer, making it an ideal biomarker for tumor-targeted therapy.

Product Specifications

Background

Claudin-18.2 is a member of the tight junction protein family. Under physiological conditions, it is only expressed at low levels in the differentiated epithelial cells of the gastric mucosa; whereas under pathological conditions, it exhibits abnormally high expression in various tumors such as gastric cancer and pancreatic cancer, making it an ideal biomarker for tumor-targeted therapy.

Specifications

This protein carries a polyhistidine tag at the N-terminus and a Flag tag at the C-terminus followed by an Avi tag (Avitag™) . The protein has a calculated MW of 26.8 kDa. The protein migrates as 25 kDa,40 kDa and 43-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P56856-2

Expression Region

Met 1 - Ala 200

Host

Insect Cells

Target

Claudin-18.2

Conjugation

Biotin-labeled

Tag

N-10xHis & C-Flag & C-Avi

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Biotinylated Human Claudin-18.2 Protein, His,Avitag&Flag Tag (Cat. No. CL2-H85D3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-Claudin-18.2 Antibody with a linear range of 0.1-2 ng/mL (QC tested).

Format

Liquid

Buffer

50 mM HEPES, 150 mM Nacl, DDM, CHS, pH7.5

Additives

Glycerol

Molecular Weight

26.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

100ug*1

Host or Source

InsectCells

Species

Human

Protein ID

P56856-2

Preservative

Glycerol

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