DCDAPH
Product Specifications
UNSPSC Description
DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid (Aβ) plaques (λex/λem=597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates (Ki=37 nM, Kd=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo[1].
Target Antigen
Amyloid-β
Type
Dye Reagents
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dcdaph.html
Solubility
10 mM in DMSO
Smiles
CN(C1=CC=C(/C=C/C=C/C=C(C#N)/C#N)C=C1)C
Molecular Weight
249.31
References & Citations
[1]Mengchao Cui, et al. Smart near-infrared fluorescence probes with donor-acceptor structure for in vivo detection of β-amyloid deposits. J Am Chem Soc. 2014 Mar 5;136(9):3388-94.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D1684/DCDAPH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D1684/
Clinical Information
No Development Reported
CAS Number
125113-96-4
Curated Selection
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