REPS1 (phospho-Ser709) rabbit pAb
This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
Product Specifications
Background
UniProt
Q96D71
Swiss Prot
Q96D71
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized phosho peptide around human REPS1 (Ser709)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
80kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
80kD
Fragment
IgG
Subcellular Location
Membrane, clathrin-coated pit . Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.
Other Product Names
RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)
Gene ID (Human)
85021
Available Sizes
Frequently Asked Questions
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