Tepilamide fumarate

Tepilamide fumarate (XP-23829; PPC-06) is an oral fumaric acid ester, acts as a proagent ofMonomethyl fumarate (HY-103252), and is used in the research of moderate to severe chronic plaque psoriasis. Tepilamide fumarate can enhance the effectiveness of oncolytic viruses[1][2].

Product Specifications

CAS Number

[1208229-58-6]

Product Name Alternative

XP-23829; PPC-06

UNSPSC

12352211

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tepilamide-fumarate.html

Purity

99.77

Solubility

DMSO : ≥ 125 mg/mL|H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(OCC(N(CC)CC)=O)/C=C/C(OC)=O

Molecular Formula

C11H17NO5

Molecular Weight

243.26

References & Citations

[1]Mrowietz U, et al. Tepilamide Fumarate (PPC-06) Extended Release Tablets in Patients with Moderate-to-Severe Plaque Psoriasis: Safety and Efficacy Results from the Randomized, Double-blind, Placebo-controlled AFFIRM Study. J Clin Aesthet Dermatol. 2022 Jan;15 (1) :53-58.|[2]Akram Alwithenani, et al. Tepilamide Fumarate as a Novel Potentiator of Virus-Based Therapy. Viruses. 2024 Jun 5;16 (6) :920.