Tepilamide fumarate
Product Specifications
UNSPSC Description
Tepilamide fumarate (XP-23829; PPC-06) is an oral fumaric acid ester, acts as a proagent of Monomethyl fumarate (HY-103252), and is used in the research of moderate to severe chronic plaque psoriasis. Tepilamide fumarate can enhance the effectiveness of oncolytic viruses[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tepilamide-fumarate.html
Purity
99.77
Solubility
DMSO : ≥ 125 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(OCC(N(CC)CC)=O)/C=C/C(OC)=O
Molecular Weight
243.26
References & Citations
[1]Mrowietz U, et al. Tepilamide Fumarate (PPC-06) Extended Release Tablets in Patients with Moderate-to-Severe Plaque Psoriasis: Safety and Efficacy Results from the Randomized, Double-blind, Placebo-controlled AFFIRM Study. J Clin Aesthet Dermatol. 2022 Jan;15(1):53-58.|[2]Akram Alwithenani, et al. Tepilamide Fumarate as a Novel Potentiator of Virus-Based Therapy. Viruses. 2024 Jun 5;16(6):920.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-109105/Tepilamide-fumarate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-109105/Tepilamide-fumarate-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1208229-58-6
Available Sizes
Curated Selection
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