JH-LPH-107

JH-LPH-107 is a LpxH inhibitor. JH-LPH-107 exhibits a low rate of spontaneous resistance and a high safety window in vitro.[1].

Product Specifications

CAS Number

[3053068-92-8]

UNSPSC

12352211

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/jh-lph-107.html

Smiles

O=C(NC1=CC=C(S(=O)(N2CCN(C3=NC(Cl)=CC(C(F)(F)F)=C3)CC2)=O)C=C1)C4=CC=CC=C4N(C)S(=O)(C)=O

Molecular Formula

C25H25ClF3N5O5S2

Molecular Weight

632.07

References & Citations

[1]Ennis AF, et al. Design and Evaluation of Pyridinyl Sulfonyl Piperazine LpxH Inhibitors with Potent Antibiotic Activity Against Enterobacterales. JACS Au. 2024 Nov 11;4 (11) :4383-4393.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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