Clomethiazole
Chlormethiazole is an potent and orally active GABAA agonist[1]. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus[2].
Product Specifications
CAS Number
[533-45-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335, H412
Target
Cytochrome P450; GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/clomethiazole.html
Concentration
10mM
Purity
99.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(CCCl)SC=N1
Molecular Formula
C6H8ClNS
Molecular Weight
161.65
Precautions
H302, H315, H319, H335, H412
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
CYP2
Available Sizes
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