Flubendazole (Standard)
Flubendazole (Standard) is the analytical standard of Flubendazole. This product is intended for research and analytical applications. Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites[1][2].
Product Specifications
CAS Number
[31430-15-6]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Apoptosis; Autophagy; MDM-2/p53; Microtubule/Tubulin; Parasite; Reference Standards; STAT
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Cytoskeleton; JAK/STAT Signaling; Others; Stem Cell/Wnt
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/flubendazole-standard.html
Smiles
O=C(OC)NC1=NC2=CC=C(C(C3=CC=C(F)C=C3)=O)C=C2N1
Molecular Formula
C16H12FN3O3
Molecular Weight
313.28
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0294R/Flubendazole-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0294R/
Scientific Category
Reference Standards
Available Sizes
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