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Puromycin HCl

Translation inhibitor

Product Specifications

Background

Puromycin is an antibiotic that is a protein synthesis inhibitor that causes premature chain termination during translation taking place in the ribosome. Part of the molecule resembles the 3' end of the tRNA. It enters the A site and transfers to the growing chain, causing the premature release. It is not selective for either prokaryotes or eukaryotes.

CAS Number

58-58-2

Product Name Alternative

3'-Deoxy-N, N-dimethyl-3'-[ (O-methyl-L-tyrosyl) amino]adenosine

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cancer | Apoptosis

Purity

>98% (TLC; HPLC) ; NMR (Conforms)

Weight

0.05

Format

Off-white powder

Solubility

May be dissolved in DMSO (50 mg/ml); or water (50 mg/ml)

Molecular Formula

C22H29N7O5•2HCl

Molecular Weight

544.43

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1.  Azzam and Algranati. (1973) Proc Natl Acad Sci. 70: 3866.

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