Thyroxine sulfate

Thyroxine sulfate is a thyroid hormone metabolite.

Product Specifications

CAS Number

[77074-49-8]

Product Name Alternative

T4 Sulfate

UNSPSC

12352005

Target

Drug Metabolite; Endogenous Metabolite; Thyroid Hormone Receptor

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Thyroxine_sulfate.html

Purity

99.84

Solubility

DMSO : 140 mg/mL (ultrasonic)

Smiles

N[C@@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(OS(=O)(O)=O)C(I)=C2)C(O)=O

Molecular Formula

C15H11I4NO7S

Molecular Weight

856.93

References & Citations

[1]Wu SY, et al. Identification of thyroxine-sulfate (T4S) in human serum and amniotic fluid by a novel T4S radioimmunoassay. Thyroid. 1992 Summer;2 (2) :101-5.|[2]Rutgers M, et al. Effects of propylthiouracil on the biliary clearance of thyroxine (T4) in rats: decreased excretion of 3,5,3'-triiodothyronine glucuronide and increased excretion of 3,3',5'-triiodothyronine glucuronide and T4 sulfate. Endocrinology. 1989 Oct;125 (4) :2175-86.|[3]Peeters RP, et al. Increased thyroxine sulfate levels in critically ill patients as a result of a decreased hepatic type Ideiodinase activity. J Clin Endocrinol Metab. 2005 Dec;90 (12) :6460-5.