NH2-PEG7
NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6[1].
Product Specifications
CAS Number
[1425973-14-3]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh2-peg7.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCOCCOCCOCCOCCOCCOCCN
Molecular Formula
C14H31NO7
Molecular Weight
325.40
Precautions
H315, H319, H335
References & Citations
[1]Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15 (12) :1223-1231.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
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