ML162-yne
Product Specifications
UNSPSC Description
ML162-yne is a potent GPX4-inhibitor affinity probe[1]. ML162-yne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
Glutathione Peroxidase
Type
Reference compound
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ml162-yne.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(N(C1=CC=C(C(Cl)=C1)OCC#C)C(CCl)=O)C2=CC=CS2)NCCC3=CC=CC=C3
Molecular Weight
501.42
References & Citations
[1]Eaton JK, et al. Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles. Nat Chem Biol. 2020 May;16(5):497-506.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153748/ML162-yne-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153748/ML162-yne-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2883115-46-4
Available Sizes
Curated Selection
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