L-NMMA
L-NMMA (Tilarginine; Methylarginine) competitively antagonizes L-arginine, and thus inhibits production of nitric oxide (NO) . L-NMMA is utilized as NO synthase antagonist in experimental settings[1].
Product Specifications
CAS Number
[17035-90-4]
Product Name Alternative
Tilarginine; Methylarginine
UNSPSC
12352211
Hazard Statement
H302, H312, H332
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/l-nmma.html
Purity
99.43
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
OC([C@@H](N)CCCNC(NC)=N)=O
Molecular Formula
C7H16N4O2
Molecular Weight
188.23
Precautions
H302, H312, H332
References & Citations
[1]Frey C, et al., L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases. J Biol Chem. 1994 Oct 21;269 (42) :26083-91.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 4
Citation 01
Available Sizes
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