2'-Hydroxyflavanone

2'-Hydroxyflavanone is a flavanone that can inhibit cancer cell proliferation, induce apoptosis, and reduce inflammation. 2'-Hydroxyflavanone shows inhibitory effect on platelet aggregation caused by two inducers with IC50s 47.8 μM arachidonic acid (AA) and 147.2 μM aenosine diphosphate (ADP) [1].

Product Specifications

CAS Number

[17348-76-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2-hydroxyflavanone.html

Concentration

10mM

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1CC(C2=CC=CC=C2O)OC3=CC=CC=C13

Molecular Formula

C15H12O3

Molecular Weight

240.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Khaled Alkadi, et al. Antiplatelet aggregation activity of 5-Hydroxyflavone, 2’-Hydroxyflavanone, Paeonol and bergenin isolated from stem bark of Garcinia malaccensis in human whole blood. September 2013Oriental Journal Of Chemistry 29 (03) :871-875