Gliadin p31-43
Gliadin p31-43 is an undigested gliadin peptide. Gliadin p31-43 induces an innate immune response in the intestine and interferes with endocytic trafficking. Gliadin p31-43 can be used for celiac disease research[1][2].
Product Specifications
CAS Number
[176326-01-5]
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gliadin-p31-43.html
Purity
98.18
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N2[C@@H](CCC2)C(N[C@H](C(O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)[C@H]4N(CCC4)C([C@H](CC5=CC=CC=C5)NC([C@H]6N(CCC6)C([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC(CNC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C71H102N18O20
Molecular Weight
1527.68
References & Citations
[1]Merlin Nanayakkara, et al. P31-43, an undigested gliadin peptide, mimics and enhances the innate immune response to viruses and interferes with endocytic trafficking: a role in celiac disease. Sci Rep. 2018 Jul 17;8 (1) :10821.|[2]María Florencia Gómez Castro, et al. p31-43 Gliadin Peptide Forms Oligomers and Induces NLRP3 Inflammasome/Caspase 1- Dependent Mucosal Damage in Small Intestine. Front Immunol. 2019 Jan 30;10:31.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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