Etevritamab
Etevritamab (AMG-596) is a bispecific T-cell engager targeting EGFRvIII and CD3. Etevritamab can simultaneously bind to the tumor-specific antigen EGFRvIII on glioblastoma multiforme and CD3 on T cells, thereby activating T-cell proliferation and secretion of cytotoxic substances to induce lysis of the bound tumor cells. Etevritamab can be used for the research of tumors such as glioblastoma multiforme[1][2].
Product Specifications
CAS Number
2329692-74-0
Product Name Alternative
AMG-596
UNSPSC
12352203
Target
CD3; EGFR
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/etevritamab.html
Purity
97.00
Smiles
[Etevritamab]
Molecular Weight
(54.66 kDa)
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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