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BHMT2 Polyclonal Antibody

Product Specifications

Background

Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

BHMT2

UniProt

Q9H2M3

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human BHMT2

Target

Betaine homocysteine methyltransferase 2; Betaine homocysteine S methyltransferase 2; EC 2.1.1.5; FLJ20001 ; S methylmethionine homocysteine S methyltransferase BHMT2; SMM hcy methyltransferase

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Purification

Antigen affinity purification

Concentration

0.6 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/lrklws

Product MSDS

https://789.bio/eb/mnD8OS

Calculated Molecular Weight

40 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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