PR (phospho Ser294) Polyclonal Antibody

Rabbit Anti-PR (phospho Ser294) Polyclonal Antibody

Product Specifications

Background

PGR (progesterone receptor) encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

CAS Number

9007-83-4

Product Name Alternative

PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3

Gene ID

5241

Accession Number

P06401

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human PR around the phosphorylation site of S294

Clonality

Polyclonal

Tag

Progesterone receptor

Applications

WB, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

98kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Phospho-PR (S294) Polyclonal Antibody detects endogenous levels of PR protein only when phosphorylated at S294.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300