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CD329 Polyclonal Antibody

Rabbit Anti-CD329 Polyclonal Antibody

Product Specifications

Background

Sialic acid-binding immunoglobulin (Ig) -like lectins, or SIGLECs (e. G. CD33 (MIM 159590) ), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13. -q13. and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al. 2000 [PubMed: 11095983]) .

CAS Number

9007-83-4

Product Name Alternative

SIGLEC8; SAF2; Sialic acid-binding Ig-like lectin 8; Siglec-8; CDw329; Sialoadhesin family member 2; SAF-2; CD329

Gene ID

27181

Accession Number

Q9NYZ4

Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of human CD329

Clonality

Polyclonal

Tag

Sialic acid-binding Ig-like lectin 8

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

50kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

CD329 Polyclonal Antibody detects endogenous levels of CD329 protein.

Observed Molecular Weight

50

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.

Other Product Names

SIGLEC8; SAF2; Sialic acid-binding Ig-like lectin 8; Siglec-8; CDw329; Sialoadhesin family member 2; SAF-2; CD329

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q9NYZ4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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