GABAA Rε Polyclonal Antibody

Rabbit Anti-GABAA Rε Polyclonal Antibody

Product Specifications

Background

The product of GABRE belongs to the ligand-gated ionic channel (TC 1. A.) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein.

CAS Number

9007-83-4

Product Name Alternative

GABRE; Gamma-aminobutyric acid receptor subunit epsilon; GABA (A) receptor subunit epsilon

Gene ID

2564

Accession Number

P78334

Reactivity

Human, Rat

Immunogen

Synthesized peptide derived from the Internal region of human GABAA rangle: Rε

Clonality

Polyclonal

Tag

Gamma-aminobutyric acid receptor subunit epsilon

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

57kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

GABAA Rε Polyclonal Antibody detects endogenous levels of GABAA Rε protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.