SGK1-IN-1
SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM.
Product Specifications
CAS Number
[1279829-87-6]
UNSPSC
12352005
Target
SGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/SGK1-IN-1.html
Purity
99.57
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=S(C1=C(F)C=CC(Cl)=C1)(NC2=CC=C(C3=NC(NN=C4N)=C4N=C3)C=C2)=O
Molecular Formula
C17H12ClFN6O2S
Molecular Weight
418.83
References & Citations
[1]ARYL SULFONOHYDRAZIDES. WO 2013041119 A1.|[2]Halland N, et al. Discovery of N-[4- (1H-Pyrazolo[3,4-b]pyrazin-6-yl) -phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors. ACS Med Chem Lett. 2014 Oct 23;6 (1) :73-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SGK1
Available Sizes
Curated Selection
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