CLC-KA Polyclonal Antibody

Rabbit Anti-CLC-KA Polyclonal Antibody

Product Specifications

Background

CLCNKA is a member of the CLC family of voltage-gated chloride channels. The encoded protein (chloride voltage-gated channel Ka) is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for CLCNKA.

CAS Number

9007-83-4

Product Name Alternative

CLCNKA; Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1

Gene ID

1187

Accession Number

P51800

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human CLC-KA at AA range: 550-630

Clonality

Polyclonal

Tag

Chloride channel protein ClC-Ka

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

75kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

CLC-KA Polyclonal Antibody detects endogenous levels of CLC-KA protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.