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ABI3 rabbit pAb

This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

Product Specifications

Background

This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

UniProt

Q9P2A4

Swiss Prot

Q9P2A4

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein AA range: 286-336

Target

ABI3

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

40kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

40kD

Fragment

IgG

Subcellular Location

Cytoplasm . Colocalizes with PAK2 at leading edge of cells.

Gene ID (Human)

51225

Available Sizes

Curated Selection

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