ABI3 rabbit pAb
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Product Specifications
Background
Gene ID
51225
UniProt
Q9P2A4
Cellular Locus
Cytoplasm. Colocalizes with PAK2 at leading edge of cells.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein AA range: 286-336
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
40kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES11795-1.pdf
Observed Molecular Weight
40 kD
Subcellular Location
Cytoplasm . Colocalizes with PAK2 at leading edge of cells.
Gene ID (Human)
51225
SwissProt (Human)
Q9P2A4
Available Sizes
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