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PRTN3 Proteinase-3 Human

PRTN3 is a natural antigen having a molecular mass of 25kDa. PRTN3 is isolated from human peripheral blood leukocytes. Applications: Western blot with rabbit anti-PR3 antisera and mouse anti-PR3 monoclonal antibodies.

Product Specifications

Synonyms

AGP7; P29; PR-3; ACPA; C-ANCA; MBT; MBN; Leukocyte proteinase 3; Neutrophil proteinase 4; Wegener granulomatosis autoantigen; Azurophil granule protein 7; myeloblastin; Serine proteinase neutrophil

Gene Name

PRTN3

UniProt

P24158

Reactivity

Mouse

Source

Native

Applications

WB

Purification

Greater than 95% in the sum of different glycosylation isoforms according to following section as determined by SDS-PAGE and capillary electrophoresis.

Function

Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.

Shipping Conditions

Available

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

Other Gene Names

Myeloblastin

Available Sizes

Frequently Asked Questions

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