KIRR2 rabbit pAb
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016],
Product Specifications
Background
Gene ID
84063
UniProt
Q6UWL6
Cellular Locus
Cell membrane ; Single-pass type I membrane protein. Localized along the sites of the cell contacts. Colocalizes with E-Cadherin and beta-catenin..
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
77kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10959-1.pdf
Observed Molecular Weight
77 kD
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Localized along the sites of the cell contacts. Colocalizes with E-Cadherin and beta-catenin. .
Gene ID (Human)
84063
SwissProt (Human)
Q6UWL6
Available Sizes
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