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Cutamesine dihydrochloride

Product Specifications

CAS Number

165377-44-6

Target

Sigma receptor

Related Pathways

GPCR/G Protein

Purity

0.9996

Bioactivity

Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective ?1 receptor agonist (IC50: 17.4 nM) . It shows selectivity for ?1 over ?2 receptors, and inhibits angiotensin II-induced cardiomyocyte hypertrophy in vitro and attenuates myocardial hypertrophy in vivo. In a rat model of experimental stroke, it enhances brain plasticity and sensorimotor function.

Smiles

Cl.Cl.COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC

Molecular Formula

C23H32N2O2·2HCl

Molecular Weight

441.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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