ODPAT rabbit pAb

Catalytic activity: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO (2). Cofactor: Thiamine pyrophosphate. enzyme regulation: E1 activity is regulated by phosphorylation (inactivation) and dephosphorylation (activation) of the alpha subunit. function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO (2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). subunit: Tetramer of 2 alpha and 2 beta subunits. tissue specificity: Testis. Expressed in postmeiotic spermatogenic cells.