ODPAT rabbit pAb
Catalytic activity: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO (2). Cofactor: Thiamine pyrophosphate. enzyme regulation: E1 activity is regulated by phosphorylation (inactivation) and dephosphorylation (activation) of the alpha subunit. function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO (2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). subunit: Tetramer of 2 alpha and 2 beta subunits. tissue specificity: Testis. Expressed in postmeiotic spermatogenic cells.
Product Specifications
Background
Gene ID
5161
UniProt
P29803
Cellular Locus
Mitochondrion matrix.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 310-390
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
42kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10076-1.pdf
Observed Molecular Weight
42 kD
Subcellular Location
Mitochondrion matrix.
Gene ID (Human)
5161
SwissProt (Human)
P29803
Available Sizes
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