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LRSM1 rabbit pAb

This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jan 2012],

Product Specifications

Background

This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jan 2012]

UniProt

Q6UWE0

Swiss Prot

Q6UWE0

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

79kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

79kD

Fragment

IgG

Subcellular Location

Cytoplasm . Displays a punctuate distribution and localizes to a submembranal ring (PubMed:15256501) . Localizes to intracellular bacterial pathogens (PubMed:23245322) . .

Gene ID (Human)

90678

Available Sizes

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