THAM

THAM (Tris) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM is an effective amine compound for pH control in the physiological range[1].

Product Specifications

CAS Number

77-86-1

Product Name Alternative

Tris; Tris (hydroxymethyl) aminomethane

UNSPSC

12352211

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/tham.html

Purity

99.88

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic)

Smiles

OCC(CO)(N)CO

Molecular Formula

C4H11NO3

Molecular Weight

121.14

References & Citations

[1]Nahas GG, et al. Guidelines for the treatment of acidaemia with THAM. Drugs. 1998 Feb;55 (2) :191-224.|[2]Höstman S, et al. THAM reduces CO2-associated increase in pulmonary vascular resistance - an experimental study in lung-injured piglets. Crit Care. 2015 Sep 17;19 (1) :331.