SgK269 rabbit pAb

This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014],

Product Specifications

Background

Product Name Alternative

PEAK1; KIAA2002; Pseudopodium-enriched atypical kinase 1; Sugen kinase 269; Tyrosine-protein kinase SgK269

UniProt

Q9H792

Swiss Prot

Q9H792

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human SGK269. AA range:111-160

Target

SgK269

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Buffer

-20°C/1 year

Molecular Weight

195kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

195kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton . Cell junction, focal adhesion . Colocalizes with F-actin in serum-rich medium (PubMed:20534451) . Actin colocalization is reduced during serum starvation (PubMed:20534451) . .