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Epsin 3 rabbit pAb

Induction: In keratinocytes, by wounding or contact with collagen. similarity: Belongs to the epsin family. similarity: Contains 1 ENTH (epsin N-terminal homology) domain. similarity: Contains 2 UIM (ubiquitin-interacting motif) repeats. subcellular location: Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus. tissue specificity: Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.

Product Specifications

Background

Induction:In keratinocytes, by wounding or contact with collagen., similarity:Belongs to the epsin family., similarity:Contains 1 ENTH (epsin N-terminal homology) domain., similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats., subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus., tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.

Synonyms

EPN3; Epsin-3; EPS-15-interacting protein 3

Gene ID

55040

UniProt

Q9H201

Cellular Locus

Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human EPN3. AA range:401-450

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

68kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6699-1.pdf

Observed Molecular Weight

68 kD

Subcellular Location

Cytoplasm . Cytoplasm, perinuclear region . Cytoplasmic vesicle, clathrin-coated vesicle . Nucleus . Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.

Other Product Names

EPN3; Epsin-3; EPS-15-interacting protein 3

Gene ID (Human)

55040

SwissProt (Human)

Q9H201

Available Sizes

Curated Selection

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