RAPSN Polyclonal Antibody

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

43 kD receptor associated protein of the synapse;43 kDa postsynaptic protein;43 kDa receptor-associated protein of the synapse; Acetylcholine receptor associated 43 kda protein ; Acetylcholine receptor-associated 43 kDa protein; CMS1D; CMS1E; MGC3597; RAPSN; RAPSN; RAPsyn; Receptor associated protein of the synapse 43kD; Receptor associated protein of the synapse; RING finger protein 205; RNF 205; RNF205